Clinical Methods

Chemical Biotypes of Psychosis

Undermethylation

Undermethylation (or histadelia) is the dominant chemical imbalance in about 20% of patients diagnosed with psychosis. The major psychotic feature is usually delusions, although auditory hallucinations are sometimes present. Laboratory indications include whole-blood histamine above 70 mg/ml and folate overload.

Most undermethylated persons in the general population tend to be high-achiever in good mental health. However, about 20% of persons diagnosed with mental illness exhibit this imbalance which responds to methylation therapies. The following is a list of factors associated with undermethylation. The presence of 30-50% of the factors may be sufficient for diagnosis.

delusions (thought disorder)
blood histamine above 70 ng/ml
absolute basophils above 50>M
self-motivated during school years
very high libido
diagnosis of delusional disorder
good response to antihistamines
high fluidity (tears, saliva, etc.)
good response to SSRI’s
high accomplishment before onset
adverse reaction to B-complex vitamins
sparse chest/leg/arm hair
suicidal tendencies
addictiveness
phobias
infrequent and terse speech
peptic ulcers
denial of illness
non-compliance with therapies
belief that CIA or FBI is after them
attempt to hide the illness
5-10% incidence of hearing voices
Tourette’s Syndrome symptoms
rumination about past events

obsessive/compulsive tendencies
history of perfectionism
low-normal serum copper
seasonal inhalant allergies
diagnosis of schizoaffective disorder
adverse reaction to benzodiazepines
low tolerance for pain
catatonic behavior during illness onset
very strong willed
slenderness
history of competitiveness in sports
large nose and ears
prior diagnosis of OCD or ODD
ritualistic behaviors
calm demeanor, but high inner tension
frequent headaches
family history of high accomplishment
blankminded appearance
poor concentration endurance
social isolation
belief that a friend or relative is an alien
gravitation toward vegetarian diets
high preponderance of male relatives
dietary inflexibility

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Clinical Methods

Chemical Biotypes of Psychosis

Undermethylation